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Homeopathy: A Healthier Way To Treat Depression?

Dr. Luc Montagnier, Nobel Prize Winner, Takes Homeopathy Seriously

Clinical Studies On Oscillococcinum

Homeopathy: A Healthier Way To Treat Depression?

huffington post September 29, 2010

By Dana Ullman

-Depression lowers the spirits and drowns the eyes in sorrow, though tears aren't the only reason why depressed people sometimes can't see straight. Depression also caves in the chest, slumps the shoulders, and inhibits full breathing, usually forcing unhappy people to try to catch their breath by frequent sighing. It is sometimes said that depression brings you down to sighs (my apology to those readers who get depressed by bad puns).

On a much more serious note, depression can be a temporary passing experience or a deeply disturbing condition that may lead to suicide. Except in cases of minor depressive states, professional attention is generally recommended to help a person go through this emotional experience in a conscious manner.

The Real Dangers of Conventional Medical Treatment

Recent studies published in leading medical journals have seriously questioned the efficacy of conventional pharmaceutical treatment of people with mild or moderate depression.

In early 2010, major media reported on a significant review of research testing antidepressant medications. (1) What is unique about this review of research is that the researchers evaluated studies that were submitted to the U.S. Food and Drug Administration (FDA), though the researchers discovered that many studies submitted to the FDA were unpublished (they found that the unpublished research consistently showed negative results of antidepressants).

This meta-analysis of antidepressant medications found only modest benefits over placebo treatment in published research, but when unpublished trial data is included, the benefit falls below accepted criteria for clinical significance.

Perhaps most startling about this research is the fact the FDA only requires drug manufacturers to provide them with two positive studies on depression to attain FDA-approval status, even if these same drug companies submit many more studies with negative results. Such information forces consumers to question the efficacy of "FDA approved drugs," and it explains why so many conventional medications eventually get withdrawn from marketplace.

At the same time that the above review research was published, another review of research was published in *JAMA* (*Journal of the American Medical Association*), and they found similar results, "The magnitude of benefit of antidepressant medication compared with placebo increases with severity of depression symptoms and may be minimal or nonexistent, on average, in patients with mild or moderate symptoms." (2) These researchers did find benefits from the use of antidepressants in the treatment of severe depression, but because the majority of people taking antidepressants today do not have "severe depression," it is prudent for many people with depression to talk to their doctors about safer and more effective alternatives.

Sadly (and strangely), when conventional doctors today do not obtain adequately effective results with one drug, they often simply prescribe more drugs in hopes that one of them, or their combination, will be more effective (whether this increased use of drugs is effective or not, there are certain "benefits" that drug companies receive from this strategy). However, increasing research is finding that "polypharmacy" (the use of multiple drugs concurrently) may lead to worse, not better, results. New research has shown that polypharmacy with psychotropic medications in suicidal adolescent inpatients has been linked to a significantly increased risk for early readmission. (3)

Presented at Ohio State University and Nationwide Children's Hospital, the researchers found that suicidal adolescent inpatients receiving three or more different classes of psychotropic medications had a 2.6-fold increased risk of being re-admitted within 30 days of discharge.

Cynthia A Fontanella, PhD, the lead researcher, asserted, "Our finding that polypharmacy was associated with an increased risk of readmission is concerning, although not surprising." Even though the serious problems with polypharmacy are known and expected, polypharmacy is growing in mental health care, not decreasing.

Other researchers discovered a disturbing trend among the over 13,000 visits of outpatients with mental disorder diagnoses: the number of psychotropic medications prescribed increased in successive years. Visits in which two or more medications were prescribed increased from 42.6 percent in 1996-1997 to 59.8 percent in 2005-2006, and those in which at least 3 medications were prescribed virtually doubled from 16.9 percent to 33.2 percent. (4)

Why Mental Illness is Increasing

There are numerous theories for why the number of people suffering from mental illness is increasing and why it is afflicting people at younger and younger ages. The homeopathic analysis for this epidemic is unique and may provide additional insight as to why this is occurring.

Like most observers of health and medicine today, homeopaths do not believe that there is simply one reason for the increase in mental illness, though many homeopaths assert that iatrogenesis (doctor-induced disease) plays a much greater role than is commonly recognized.

Homeopaths, like modern-day physiologists, understand that symptoms of illness represent the body's defenses in its efforts to adapt to and respond against infection, environmental assault, or stress of some kind. As discomforting as symptoms can be, they still represent the living organism's best efforts at the time to try to defend and heal him or herself. Such defenses are an innate part of our evolutionary efforts to survive. The symptoms that a person experiences are a part of the body's innate wisdom, commonly referred to as "*vis mediatrix naturae*" (the healing power of nature).

Using conventional medications to inhibit or suppress a symptom may be effective temporarily, but THIS is often the "bad news." Because symptoms as diverse as fevers, coughs, nasal discharges, or even high blood pressure are recognized by physiologists as adaptations and defenses of the body, drugs that inhibit these symptoms may provide a short-term benefit, but such drugs also reduce the person's ability to get over the illness. More significantly and more seriously, conventional medications may actually suppress the disease process and the wisdom of the body, thereby creating a deeper and more serious illness.

The irony to "modern scientific medicine" is that the evidence that doctors proudly show that a drug "works" is often actually evidence that the drug is effective in suppressing, not curing, a specific symptom (there are, of course, many exceptions to this general observation, such as antibiotics, but antibiotic drugs create other problems about which this writer and many others have commented already).

For over 200 years homeopaths have observed the ability of many conventional drugs to suppress acute illness into more deep chronic illness. During this time, homeopaths have also found that this disease suppression also creates more and greater mental illness. When reviewing the side-effects of many drugs, it is not uncommon to find that drugs are known to lead to various states of mental illness from depression to delusion to suicidal propensities.

Just as suppressing one's emotions often leads to a later explosion of these emotions to someone who happens to be at the wrong place at the wrong time, suppressing physical symptoms can lead to a more serious physical disease or a more disturbing mental illness. Using drugs to provide temporary relief does not have some type of cost, and the cost is usually a later and more serious ailment.

Homeopathic Treatment of Depression

The Menninger Clinic is world-renowned as one of the leading mental health centers for research and treatment. Most people don't know it, but the founder of the Menninger Clinic, Charles Frederick Menninger, MD, was originally a homeopathic physician. He was even the head of his local homeopathic medicine society and was so frequently impressed with the results that he got from homeopathic medicines, he once said, "Homeopathy is wholly capable of satisfying the therapeutic demands of this age better than any other system or school of medicine." (5)

Numerous studies have shown benefits in using the herb, St. Johns wort, to treat mild to moderate depression. However, homeopaths generally find that it is preferable to prescribe individualized homeopathic remedies to each patient to attain better long-term sustained results without having to take continual doses of any medicine (natural or otherwise). In fact, a recent study published in a medical journal published by Oxford University Press found that individualized homeopathic treatment is as effective and is safer than Prozac in the treatment of people with moderate or severe depression. (6)

This study included 91 outpatients with moderate to severe depression who received an individually chosen homeopathic medicine or fluoxetine (Prozac) 20 mg/day (up to 40 mg/day) in a prospective, randomized, double-blind double-dummy eight week trial. The primary efficacy measure was the mean change in MADRS depression scores (MADRS is a commonly used observer rated depression scale, with a score of 32 representing the "severe depression"). The average MADRS of patients in this study was 29. The mean MADRS scores differences were not significant on the fourth (p=0.654) and eigth weeks (p=0.965) of treatment, which suggests that the two methods of treatment are equally effective. There were also no significant differences between the percentages of response or remission rates in both groups. The study also found a higher but non-significant percentage of patients treated with Prozac reported troublesome side effects, and there was a trend toward greater treatment interruption for adverse effects in the Prozac group.

Those people who claim to be "skeptics" of homeopathy will be surprised and impressed to know that two specialty medical journals published a double-blind and placebo controlled study on mice and found that one of the medicines in the above study, Gelsemium sempervirens, had anxiety-related effects. (7)(8)

Jonathan Davidson, MD, a professor of psychiatry at Duke University, conducted a small study of adults with major depression, social phobia, or panic disorder. He found that 60 percent of the patients responded favorably to homeopathic treatment. (9) When one recognizes the considerable safety of homeopathic medicines and the benefits that some patients get from this safer method of treatment, it is remarkable that the majority of psychiatrists and psychologists do not yet refer appropriate patients to homeopaths prior to prescribing powerful conventional drugs for them.

A clinical outcome study of interest involved 14 physicians of the United Kingdom's Faculty of Homeopathy (13 NHS GPs and 3 private practitioners) who treated a wide variety of people with chronic ailments. (10) The outcome scores from 958 individual patient conditions having two or more appointments found that 75.9 percent experienced a "positive outcome," 14.7 percent had no change, and 4.6 percent experienced deterioration in health. Patients with the highest positive scores (over 50 percent of patients who self-scored a +2 or +3 on a 7 point Likert scale from -3 to +3) were achieved in the treatment of anxiety, catarrh, colic, cystitis, depression, eczema, irritable bowel syndrome, and PMS. A total of 63.6 percent of patients with depression self-scored a +2 or +3 result from homeopathic treatment.

More information on the homeopathic treatment of mental illness and more scientific evidence verifying its efficacy is contained in a newly published textbook on the subject, Homeopathy and Mental Health Care: Integrative Practice, Principles, and Research http://www.amazon.com/Homeopathy-Mental-Health-Care-Integrative/dp/9490453013/ref=sr_1_1?s=books&ie=UTF8&qid=1279828596&sr=1-1

How NOT to Use Homeopathy for Depression

In early 2010, Alexa Ray Joel, the daughter of singer Billy Joel and actress/model Christy Brinkley, supposedly tried to kill herself by taking a homeopathic medicine, called Traumeel. Anyone with the simply elementary knowledge of homeopathy knows that one cannot commit suicide taking homeopathic medicines due to the extremely small doses in these medicines. Even homeopathy's most ardent skeptics must have had a good laugh at this media report.

After the initial media report about Alexa Ray Joel's suicide attempt, she went public with the fact that she suffered from depression as a result of a break-up in a relationship. And yet, Ms. Joel did not correct the misunderstanding of homeopathic medicine or the assertions made claiming that she (or anyone) could kill themselves with a homeopathic remedy. Sympathy is certainly appropriate for anyone who experiences such emotional trauma from the break-up of a love relationship to consider suicide. However, we should be wary of actions that inappropriately seek to tarnish the reputation of good companies or safe medicines.

Why Homeopathy Makes Sense for Depression

Homeopathic medicines are not prescribed based on the person's diagnosed disease but on the unique way the person experiences his or her disease. In other words, homeopathic medicines are prescribed based on the SYNDROME of various physical and psychological symptoms, not just a single symptom or disease label. Although the selection of the correct homeopathic prescribing is more complex than the use of conventional drugs or even many herbal preparations, the system of prescribing that is individualized to the whole person is intellectually sound... and its results are often significant if not substantial.

The premise behind homeopathy is that symptoms of illness are not just something "wrong" with the person but are actually efforts of their bodymind to fight infection and/or to adapt to stress. Instead of using large doses of pharmacological agents to inhibit or suppress symptoms, very small and specially prepared doses of medicinal substances are individually prescribed to a person for their unique ability to cause in overdose the similar symptoms that the sick person is having. By finding a medicine that matches the symptoms of the sick person, the medicine supports and augments the body's defenses. Ultimately, homeopathy is what Stewart Brand, founder of the “Whole Earth Catalog”, called "medical aikido" because it goes with, rather than against, the force of the disease. It is also a type of "medical biomimicry."

There is, indeed, much more that could be said about the sophisticated system of healing that homeopathy embodies and on the historical and scientific evidence that verifies its safety and efficacy, but the above information and insights provide a good introduction to why people with mild to moderate depression might be considering seeking professional homeopathic care.

REFERENCES:

(1) Kirsch I, Deacon BJ, Huedo-Medina TB, Scoboria A, Moore TJ, et al. (2008) Initial Severity and Antidepressant Benefits: A Meta-Analysis of Data Submitted to the Food and Drug Administration. PLoS Med 5(2): e45. doi:10.1371/journal.pmed.0050045

http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.0050045

(2) Fournier JC, DeRubeis RJ, Hollon SD, Dimidjian S, Amsterdam JD, Shelton RC, Fawcett J. Antidepressant Drug Effects and Depression Severity: A Patient-Level Meta-analysis. JAMA. 2010;303(1):47-53.

http://jama.ama-assn.org/cgi/content/short/303/1/47?home

(3) Fontanella CA, Bridge JA, Campo JV. Psychotropic medication changes, polypharmacy, and the risk of early readmission in suicidal adolescent inpatients. Ann Pharmacother. 2009 Dec;43(12):1939-47.

(4) Mojtabai R, Olfson M. National Trends in Psychotropic Medication Polypharmacy in Office-Based Psychiatry. Arch Gen Psychiatry. 2010;67:26-36.

(5) Menninger, C. F. The Application as Well as the Similar, Transactions of the American Institute of Homeopathy, 1896, pp. 317-324.

(6) Adler UC, Paiva NMP, Cesar AT, Adler MS, Molina A, Padula AE, Calil HM. Homeopathic individualized Q-potencies versus fluoxetine for moderate to severe depression: double-blind, randomized non-inferiority trial. Evid Based Complement Alternat Med. 2009 Aug 17.

http://ecam.oxfordjournals.org/cgi/content/full/nep114v1

(7) Bellavite P, Magnani P, Zanolin E, Conforti A. Homeopathic Doses of Gelsemium sempervirens Improve the Behavior of Mice in Response to Novel Environments. Evid Based Complement Alternat Med. 2009 Sep 14.

http://www.ncbi.nlm.nih.gov/pubmed/19752165?dopt=Abstract

(8) Magnani P, Conforti A, Zanolin E, Marzotto M, Bellavite P. Dose-effect study of Gelsemium sempervirens in high dilutions on anxiety-related responses in mice. Psychopharmacology (Berl). 2010 Apr 20.

(9) Davidson, J, Morrison, R, Shore, J, et al., Homeopathic Treatment of Depression and Anxiety," Alternative Therapies, January, 1997,3,1:46-49.

(10) Mathie, RT, Robinson, TW. Outcomes from Homeopathic Practice in Medical Practice: A Prospective, Research-Tarageted, Pilot Study, Homeopathy. 2006,95:199-205.

Dana Ullman, MPH, is America's leading spokesperson for homeopathy and is

the founder of

http://www.homeopathic.com%20.%20

He is the author of 10 books, including his bestseller, *Everybody's Guide to Homeopathic Medicines. His latest book is, *The Homeopathic Revolution: Why Famous People and Cultural Heroes Choose

Homeopathy. * the Foreword to this book was written by Dr. Peter Fisher, the Physician To Her Majesty Queen Elizabeth II). Dana lives, practices, and writes from Berkeley, California.

Dr. Luc Montagnier, Nobel Prize Winner, Takes Homeopathy Seriously

Posted: January 30, 2011 11:49 AM

http://www.homeopathic.com%20.%20

Dr. Luc Montagnier, the French virologist who won the Nobel Prize in 2008 for discovering the AIDS virus, has surprised the scientific community with his strong support for homeopathic medicine.

In a remarkable interview published in Science magazine of December 24, 2010, (1) Professor Luc Montagnier, has expressed support for the often maligned and misunderstood medical specialty of homeopathic medicine. Although homeopathy has persisted for 200+ years throughout the world and has been the leading alternative treatment method used by physicians in Europe, (2) most conventional physicians and scientists have expressed skepticism about its efficacy due to the extremely small doses of medicines used.

Most clinical research conducted on homeopathic medicines that has been published in peer-review journals have shown positive clinical results,(3, 4) especially in the treatment of respiratory allergies (5, 6), influenza, (7) fibromyalgia, (8, 9) rheumatoid arthritis, (10) childhood diarrhea, (11) post-surgical abdominal surgery recovery, (12) attention deficit disorder, (13) and reduction in the side effects of conventional cancer treatments. (14) In addition to clinical trials, several hundred basic science studies have confirmed the biological activity of homeopathic medicines. One type of basic science trials, called in vitro studies, found 67 experiments (1/3 of them replications) and nearly 3/4 of all replications were positive. (15, 16)

In addition to the wide variety of basic science evidence and clinical research, further evidence for homeopathy resides in the fact that they gained widespread popularity in the U.S. and Europe during the 19th century due to the impressive results people experienced in the treatment of epidemics that raged during that time, including cholera, typhoid, yellow fever, scarlet fever, and influenza.

Montagnier, who is also founder and president of the World Foundation for AIDS Research and Prevention, asserted, "I can't say that homeopathy is right in everything. What I can say now is that the high dilutions (used in homeopathy) are right. High dilutions of something are not nothing. They are water structures which mimic the original molecules."

Here, Montagnier is making reference to his experimental research that confirms one of the controversial features of homeopathic medicine that uses doses of substances that undergo sequential dilution with vigorous shaking in-between each dilution. Although it is common for modern-day scientists to assume that none of the original molecules remain in solution, Montagnier's research (and other of many of his colleagues) has verified that electromagnetic signals of the original medicine remains in the water and has dramatic biological effects.

Montagnier has just taken a new position at Jiaotong University in Shanghai, China (this university is often referred to as "China's MIT"), where he will work in a new institute bearing his name. This work focuses on a new scientific movement at the crossroads of physics, biology, and medicine: the phenomenon of electromagnetic waves produced by DNA in water. He and his team will study both the theoretical basis and the possible applications in medicine.

Montagnier's new research is investigating the electromagnetic waves that he says emanate from the highly diluted DNA of various pathogens. Montagnier asserts, "What we have found is that DNA produces structural changes in water, which persist at very high dilutions, and which lead to resonant electromagnetic signals that we can measure. Not all DNA produces signals that we can detect with our device. The high-intensity signals come from bacterial and viral DNA."

Montagnier affirms that these new observations will lead to novel treatments for many common chronic diseases, including but not limited to autism, Alzheimer's disease, Parkinson's disease, and multiple sclerosis.

Montagnier first wrote about his findings in 2009, (17) and then, in mid-2010, he spoke at a prestigious meeting of fellow Nobelists where he expressed interest in homeopathy and the implications of this system of medicine. (18)

French retirement laws do not allow Montagnier, who is 78 years of age, to work at a public institute, thereby limiting access to research funding. Montagnier acknowledges that getting research funds from Big Pharma and certain other conventional research funding agencies is unlikely due to the atmosphere of antagonism to homeopathy and natural treatment options.

Support from Another Nobel Prize winner

Montagnier's new research evokes memories one of the most sensational stories in French science, often referred to as the “Benveniste affair.” A highly respected immunologist Dr. Jacques Benveniste., who died in 2004, conducted a study which was replicated in three other university laboratories and that was published in Nature (19). Benveniste and other researchers used extremely diluted doses of substances that created an effect on a type of white blood cell called basophils.

Although Benveniste's work was supposedly debunked, (20) Montagnier considers Benveniste a "modern Galileo" who was far ahead of his day and time and who was attacked for investigating a medical and scientific subject that orthodoxy had mistakenly overlooked and even demonized.

In addition to Benveniste and Montagnier is the weighty opinion of Brian Josephson, Ph.D., who, like Montagnier, is a Nobel Prize-winning scientist.

Responding to an article on homeopathy in New Scientist, Josephson wrote:

Regarding your comments on claims made for homeopathy: criticisms centered around the vanishingly small number of solute molecules present in a solution after it has been repeatedly diluted are beside the point, since advocates of homeopathic remedies attribute their effects not to molecules present in the water, but to modifications of the water's structure.

Simple-minded analysis may suggest that water, being a fluid, cannot have a structure of the kind that such a picture would demand. But cases such as that of liquid crystals, which while flowing like an ordinary fluid can maintain an ordered structure over macroscopic distances, show the limitations of such ways of thinking. There have not, to the best of my knowledge, been any refutations of homeopathy that remain valid after this particular point is taken into account.

A related topic is the phenomenon, claimed by Jacques Benveniste's colleague Yolène Thomas and by others to be well established experimentally, known as

"memory of water." If valid, this would be of greater significance than homeopathy itself, and it attests to the limited vision of the modern scientific community that, far from hastening to test such claims, the only response has been to dismiss them out of hand. (21)

Following his comments Josephson, who is an emeritus professor of Cambridge University in England, was asked by New Scientist editors how he became an advocate of unconventional ideas. He responded:

I went to a conference where the French immunologist Jacques Benveniste was talking for the first time about his discovery that water has a 'memory' of compounds that were once dissolved in it -- which might explain how homeopathy works. His findings provoked irrationally strong reactions from scientists, and I was struck by how badly he was treated. (22)

Josephson went on to describe how many scientists today suffer from "pathological disbelief;" that is, they maintain an unscientific attitude that is embodied by the statement "even if it were true I wouldn't believe it."

Even more recently, Josephson wryly responded to the chronic ignorance of homeopathy by its skeptics saying, "The idea that water can have a memory can be readily refuted by any one of a number of easily understood, invalid arguments."

In the new interview in Science, Montagnier also expressed real concern about the unscientific atmosphere that presently exists on certain unconventional subjects such as homeopathy, "I am told that some people have reproduced Benveniste's results, but they are afraid to publish it because of the intellectual terror from people who don't understand it."

Montagnier concluded the interview when asked if he is concerned that he is drifting into pseudoscience, he replied adamantly: "No, because it's not pseudoscience. It's not quackery. These are real phenomena which deserve further study."

The Misinformation That Skeptics Spread

It is remarkable enough that many skeptics of homeopathy actually say that there is "no research" that has shows that homeopathic medicines work. Such statements are clearly false, and yet, such assertions are common on the Internet and even in some peer-review articles. Just a little bit of searching can uncover many high quality studies that have been published in highly respected medical and scientific journals, including the Lancet, BMJ, Pediatrics, Pediatric Infectious Disease Journal, Chest and many others. Although some of these same journals have also published research with negative results to homeopathy, there is simply much more research that shows a positive rather than negative effect.

Misstatements and misinformation on homeopathy are predictable because this system of medicine provides a viable and significant threat to economic interests in medicine, let alone to the very philosophy and worldview of biomedicine. It is therefore not surprising that the British Medical Association had the sheer audacity to refer to homeopathy as "witchcraft." It is quite predictable that when one goes on a witch hunt, one inevitably finds "witches," especially when there are certain benefits to demonizing a potential competitor (homeopathy plays a much larger and more competitive role in Europe than it does in the USA).

Skeptics of homeopathy also have long asserted that homeopathic medicines have "nothing" in them because they are diluted too much. However, new research conducted at the respected Indian Institutes of Technology has confirmed the presence of "nanoparticles" of the starting materials even at extremely high dilutions. Researchers have demonstrated by Transmission Electron Microscopy (TEM), electron diffraction and chemical analysis by Inductively Coupled Plasma-Atomic Emission Spectroscopy (ICP-AES), the presence of physical entities in these extreme dilutions. (24) In the light of this research, it can now be asserted that anyone who says or suggests that there is "nothing" in homeopathic medicines is either simply uninformed or is not being honest.

Because the researchers received confirmation of the existence of nanoparticles at two different homeopathic high potencies (30C and 200C) and because they tested four different medicines (Zincum met./zinc; Aurum met. /gold; Stannum met./tin; and Cuprum met./copper), the researchers concluded that this study provides "concrete evidence."

Although skeptics of homeopathy may assume that homeopathic doses are still too small to have any biological action, such assumptions have also been proven wrong. The multi-disciplinary field of small dose effects is called "hormesis," and approximately 1,000 studies from a wide variety of scientific specialties have confirmed significant and sometimes substantial biological effects from extremely small doses of certain substances on certain biological systems.

A special issue of the peer-review journal, Human and Experimental Toxicology (July 2010), devoted itself to the interface between hormesis and homeopathy. (25) The articles in this issue verify the power of homeopathic doses of various substances.

In closing, it should be noted that skepticism of any subject is important to the evolution of science and medicine. However, as noted above by Nobelist Brian Josephson, many scientists have a "pathological disbelief" in certain subjects that ultimately create an unhealthy and unscientific attitude blocks real truth and real science. Skepticism is at its best when its advocates do not try to cut off research or close down conversation of a subject but instead explore possible new (or old) ways to understand and verify strange but compelling phenomena. We all have this challenge as we explore and evaluate the biological and clinical effects of homeopathic medicines.

REFERENCES:

(1) Enserink M, Newsmaker Interview: Luc Montagnier, French Nobelist Escapes "Intellectual Terror" to Pursue Radical Ideas in China. Science 24 December 2010: Vol. 330 no. 6012 p. 1732. DOI: 10.1126/science.330.6012.1732

(2) Ullman D. Homeopathic Medicine: Europe's #1 Alternative for Doctors.

http://www.huffingtonpost.com/dana-ullman/homeopathic-medicine-euro_b_402490.html

(3) Linde L, Clausius N, Ramirez G, et al., "Are the Clinical Effects of Homoeopathy Placebo Effects? A Meta-analysis of Placebo-Controlled Trials," Lancet, September 20, 1997, 350:834-843.

(4) Lüdtke R, Rutten ALB. The conclusions on the effectiveness of homeopathy highly depend on the set of analyzed trials. Journal of Clinical Epidemiology. October 2008. doi: 10.1016/j.jclinepi.2008.06/015.

(5) Taylor, MA, Reilly, D, Llewellyn-Jones, RH, et al., Randomised controlled trial of homoeopathy versus placebo in perennial allergic rhinitis with overview of four trial Series, BMJ, August 19, 2000, 321:471-476.

(6) Ullman, D, Frass, M. A Review of Homeopathic Research in the Treatment of Respiratory Allergies. Alternative Medicine Review. 2010:15,1:48-58.

http://www.thorne.com/altmedrev/.fulltext/15/1/48.pdf

(7) Vickers AJ. Homoeopathic Oscillococcinum for preventing and treating influenza and influenza-like syndromes. Cochrane Reviews. 2009.

(8) Bell IR, Lewis II DA, Brooks AJ, et al. Improved clinical status in fibromyalgia patients treated with individualized homeopathic remedies versus placebo, Rheumatology. 2004:1111-5.

(9) Fisher P, Greenwood A, Huskisson EC, et al., "Effect of Homoeopathic Treatment on Fibrositis (Primary Fibromyalgia)," BMJ, 299(August 5, 1989):365-6.

(10) Jonas, WB, Linde, Klaus, and Ramirez, Gilbert, "Homeopathy and Rheumatic Disease," Rheumatic Disease Clinics of North America, February 2000,1:117-123.

(11) Jacobs J, Jonas WB, Jimenez-Perez M, Crothers D, Homeopathy for Childhood Diarrhea: Combined Results and Metaanalysis from Three Randomized, Controlled Clinical Trials, Pediatr Infect Dis J, 2003;22:229-34.

(12) Barnes, J, Resch, KL, Ernst, E, "Homeopathy for Post-Operative Ileus: A Meta-Analysis," Journal of Clinical Gastroenterology, 1997, 25: 628-633.

(13) M, Thurneysen A. Homeopathic treatment of children with attention deficit hyperactivity disorder: a randomised, double blind, placebo controlled crossover trial. Eur J Pediatr. 2005 Dec;164(12):758-67. Epub 2005 Jul 27.

(14) Kassab S, Cummings M, Berkovitz S, van Haselen R, Fisher P. Homeopathic medicines for adverse effects of cancer treatments. Cochrane Database of Systematic Reviews 2009, Issue 2.

(15) Witt CM, Bluth M, Albrecht H, Weisshuhn TE, Baumgartner S, Willich SN. The in vitro evidence for an effect of high homeopathic potencies--a systematic review of the literature. Complement Ther Med. 2007 Jun;15(2):128-38. Epub 2007 Mar 28.

(16) Endler PC, Thieves K, Reich C, Matthiessen P, Bonamin L, Scherr C, Baumgartner S. Repetitions of fundamental research models for homeopathically prepared dilutions beyond 10-23: a bibliometric study. Homeopathy, 2010; 99: 25-36.

(17) Luc Montagnier, Jamal Aissa, Stéphane Ferris, Jean-Luc Montagnier, Claude Lavallee, Electromagnetic Signals Are Produced by Aqueous Nanostructures Derived from Bacterial DNA Sequences. Interdiscip Sci Comput Life Sci (2009) 1: 81-90.

http://www.springerlink.com/content/0557v31188m3766x/fulltext.pdf

(18) Nobel laureate gives homeopathy a boost. The Australian. July 5, 2010.

http://www.theaustralian.com.au/news/health-science/nobel-laureate-gives-homeopathy-a-boost/story-e6frg8y6-1225887772305

(19) Davenas E, Beauvais F, Amara J, et al. (June 1988). "Human basophil degranulation triggered by very dilute antiserum against IgE". Nature 333 (6176): 816-8.

(20) Maddox J (June 1988). "Can a Greek tragedy be avoided?". Nature 333 (6176): 795-7.

(21) Josephson, B. D., Letter, New Scientist, November 1, 1997.

(22) George A. Lone Voices special: Take nobody's word for it. New Scientist. December 9, 2006.

(23) Personal communication. Brian Josephson to Dana Ullman. January 5, 2011.

(24) Chikramane PS, Suresh AK, Bellare JR, and Govind S. Extreme homeopathic dilutions retain starting materials: A nanoparticulate perspective. Homeopathy. Volume 99, Issue 4, October 2010, 231-242.

(25) Human and Experimental Toxicology, July 2010:

http://het.sagepub.com/content/vol29/issue7/

To access free copies of these articles, see:

http://www.siomi.it/siomifile/siomi_pdf/BELLE_newsletter.pdf

Clinical Studies On Oscillococcinum

Oscillococcinum has been shown in clinical trials to help reduce the severity and shorten the duration of flu symptoms.1,2

Oscillococcinum works rapidly, with 63 percent of patients showing “complete resolution" or "clear improvement” at 48 hours. (1) In a double-blind, placebo-controlled clinical trial, the recovery rate within 48 hours of treatment was significantly greater in the group that received the active drug than in the placebo group. (2) Versus 48% in the placebo group, P=0.003; †P=0.03.

Unlike other flu medicines, Oscillococcinum does not cause side effects, such as drowsiness, and has no known or reported drug interactions. Oscillococcinum is regulated as a drug by the FDA (3) and can be purchased at pharmacies, natural food stores and supermarkets.

Make sure to keep Oscillococcinum on hand because it works best when taken early. Take Oscillococcinum at the first signs of flu-like symptoms.

REFERENCES:

1. Papp R, Schuback G, Beck E, et al. Oscillococcinum in patients with influenza-like syndromes: a placebo-controlled, double-blind evaluation. Br Homeopath J. 1998;87:69-76.

2. Ferley JP, Zmirou D, D’Adhemar D, Balducci F. A controlled evaluation of a homeopathic preparation in the treatment of influenza-like syndromes. Br J Clin Pharmacol. 1989;27:329-335.

3. U.S. Food and Drug Administration. Sec. 400.400 Conditions Under Which Homeopathic Drugs May be Marketed (CPG 7132.15).

Summary of Studies

Download a PDF summary of four double-blind, placebo-controlled clinical studies on Oscillococcinum. Included in this PDF is a chart comparing Oscillococcinum with antivirals, herbs, vitamins, and symptomatic medicines for aches and fever.

http://www.oscillo.com/site/images/assets/oscillo-monograph.pdf

Read an independent review of research studies on Oscillococcinum conducted by the Cochrane Collaboration (Cochrane Database Syst. Rev. 3: CD001957, 2006.)

http://www.oscillo.com/site/http://www.update-software.com/abstracts/ab001957.htm

“Taking Oscillococcinum at the first sign of flu symptoms reduced the average bout by about 6 hours in the two studies that provided enough data to analyze.”

-Andrew Vickers, Memorial Sloan-Kettering Cancer Center, who reviewed the

evidence on Oscillococcinum for the Cochrane Collaboration (quote published

in “Nutrition Action Healthletter”, January/February 2007)

“The research is somewhat promising. Two separate authors reviewed seven well-controlled studies that showed that it was able to reduce flu-like symptoms by about 7 hours. That doesn’t sound like a lot, but if you feel miserable, 7 hours can make a difference.”

-Joy Bauer, Joy Bauer Nutrition Center, New York,, and “Today

Show” contributor (quote heard on the “Today Show”, Feb. 13, 2007)

Picture of Lily of the Valley Flower used for treating strokes Lily of the Valley

(Convallaria Magalis)

Used to treat strokes, when speech is slow to return

Did You Know

There are over a hundred peer-reviewed scientific papers that support the efficacy and validity of homeopathic medicine.

On October 25, 2007, a debate about homeopathy

was held at the University of Connecticut Health Center. As part of this event, Iris Bell, MD, PhD presented a compelling overview of scientific evidence supporting the efficacy and validity of homeopathic medicine. Her presentation was also accompanied by an extensive literature reference list available on this site as a research article (look under the Articles Tab, Research, Peer-Reviewed Journals).

Courtesy National Center For Homeopathy

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